Your provider will typically need to submit a letter of medical necessity along with supporting documentation: your BMI, relevant lab results, any comorbidities, prior weight loss attempts, and a clear clinical argument for why this medication is appropriate for you specifically
Huge thanks to my teammate, Jean Cunningham, PharmD, who put this togetherand whose enthusiasm for GLP-1s is unmatched
You dont have to navigate a weight loss plateau alone
GLP-1 treatment can exert the direct action on reversing vascular remodeling by downregulating MMP1 expression via alleviating the ERK1/2/NF-B pathway in Ang II-induced rat aortic VSMCs [130]
In addition, some GLP-1 drugs have gotten additional FDA approvals for reduction of cardiovascular disease risk and treatment of sleep apnea and fatty liver disease (also called MASHLD and AFLD) in people with overweight or obesity
Yes, Mounjaro can be used with insulin for diabetes management, especially for people with type 2 diabetes who are overweight