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Mitochondria are referred to as the "powerhouses of the cell" because of their role in the production of ATP (adenosine triphosphate)
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thus, dose reduction strategies (e.g., taking 100 mcg from Monday to Saturday but skipping Sunday) may not have been accurately captured
Collectively, these findings emphasize the role of the hypoxic microenvironment in MS-associated fibrosis, suggesting that its regulation may represent a potential new therapeutic strategy for MS and other fibrotic diseases
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