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muciniphila research is considered promising but still emerging for human applications

Earlier formulations required frequent dosing, but newer agents like Dulaglutide and Semaglutide allow once-weekly dosing, and regulators have approved an oral Semaglutide formulation (18)(21)(27)

Board PG, Baker RT, Chelvanayagam G, Jermiin LS

The drug companies were able to make these short-acting compounds into long-acting compounds, so they only have to be injected once a week instead of daily which is a big advantage

However, several challenges remain in translating current SIRT1-targeted strategies from experimental studies to clinical application