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106 Some of them also directly derive from salivary glands

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When used with insulin or sulfonylureas, dose reductions of these medications may be needed to reduce the risk of hypoglycaemia

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If patients requiring hospitalization for Covid-19 continue on SGLT2i, they should be monitored for DKA, which can occur in patients with Covid-19 independently of treatment, but can sometimes also be associated with SGLT2i use [66][68, 108][116]