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Oxidized PAC-quinone imine metabolites have also been shown to form GSH-conjugates which inhibit glutathione reductase (GR): the decreased activity of GR hampers the detoxification and antioxidant capacity of the GSH-GSSG cycle, further aggravating the pro-oxidative status in the cell (Ndlov et al., 2014)

Inactive ingredients: Alcohol (0.1%), benzalkonium chloride, boric acid, chlorobutanol, edetate disodium, menthol, potassium aspartate, purified water, sodium borate

Although the intercellular junctions comprise ~ 0.01% of the intestinal surface area [23], paracellular transport makes an outsize contribution to the transepithelial movement of water and solutes [24]

Doesburg VM

Under normal circumstances it is produced by our bodies