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In both the intestinal epithelium and liver, they are rapidly transformed into hydrophilic metabolites through phase II enzymatic reactions such as glucuronidation, sulfation, and methylation, catalyzed by enzymes including uridine 5-diphospho-glucuronosyltransferase, sulfotransferase, and catechol- O -methyltransferase

Biomed Rep 8(5):439446

Well administer the NAD+ first via IV and then the glutathione immediately thereafter

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