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Specifically, these five GST isozymes could increase the cell viability, reduce the LDH release and ROS accumulation, and facilitate the production of AFBO-GSH, thus alleviating AFB 1 -induced DNA damage in the LMH cells

Cell 176 , 831843.e822 (2019)

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In support of this observation, over expression of GS in a yeast model failed to increase glutathione (GSH) levels whereas over expression of GCL did [18]

This is due to biotin sharing its transporter with vitamin B5, so theoretically taking high doses of one could impair uptake of the other