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Drug Res (Stuttg) 64(10):510515 Zhu J, Chen Z, Feng W, Long S, Mo ZC (2019) Sex hormone-binding globulin and polycystic ovary syndrome

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Moreover, existing studies mostly focus on the regulation of RA synovial cells (such as FLS) or macrophages by the cGAS-STING pathway, whereas this study, for the first time, clearly demonstrates the central role of the cGAS-STING-ferroptosis axis in RA chondrocytes, and reveals that GLP-1RAs exerted therapeutic effects on RA through a dual mechanism of directly inhibiting this axis and simultaneously promoting the M2 polarization of macrophages

The Journal of Physiology , 591 , 4655-4666