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Serlie, A
The New England Journal of Medicine, 389 (2), 107117
Slow titration of dose can help, as can dietary adjustments. The recent mast cell paper suggested: significantly lower doses of GLP-1RAs than presently used as starting doses for T2DM and obesity therapy might be sufficient, and even optimal, for MCAS
Key points Cardiovascular outcome trials in individuals with type 2 diabetes mellitus demonstrate that glucagon-like peptide 1 (GLP1) receptor (GLP1R) agonists reduce the rates of non-fatal myocardial infarction, non-fatal stroke and cardiovascular death
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