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Cottone: GLP-1 is a hormone that stimulates the release of insulin from the pancreatic islets and curbs hunger, among other actions

Two important targets of NRF2 are the HMOX1 (heme oxygenase 1) and NQO1 [NAD(P)H quinone oxidoreductase 1] genes

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Although the reasons for this partitioning are only partially understood, these antioxidants are considered critical in both health and disease

This finding provides a new concept of distal signaling in the gut-brain circuit for the regulation of locomotion