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As the prevalence of obesity and diabetes have reached epidemic proportions in many regions throughout the world (15), such findings underscore the urgent need for targeted therapies addressing brain health in the face of high fat diets, especially during middle age - a period critical for metabolic and cognitive health

All potential biotargets of L-carnitine in PCOS treatment were methodically obtained using a promising bioinformatic assay, and the potential core pharmacological targets were identified as PIK3R1 , MAPK1 , HIF-1A , TLR-4 , SRC , and EP300

Other genetic variations which increase the risk of side effects (COMT, MAOA)

Most studies were urban-based

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