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We highlight the dynamic regulation of nuclear l-lactyl-CoA and l-lactyl-CoA synthetases, which are crucial determinants of the specificity of histone Lys l-lactylation

The SELECT trial enrolled 17,604 patients with a mean body mass index (BMI) of 33.3 and preexisting cardiovascular disease (prior heart attack, stroke, or peripheral artery disease) but no diabetes

After the stabilization period, the hearts were subjected to 20 min of total ischemia followed by 40 min reperfusion

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