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Summary Keywords stress response, redox homeostasis, transcription, purine nucleotide, glutathione Citation Mitsuishi Y, Motohashi H and Yamamoto M (2012) The Keap1Nrf2 system in cancers: stress response and anabolic metabolism

ISSLS prize winner: A study of diffusion in human lumbar discs: a serial magnetic resonance imaging study documenting the influence of the endplate on diffusion in normal and degenerate discs

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**Neuropsychiatric Effects**: Chronic hypoglycemia may lead to cognitive dysfunction, affecting memory, concentration, and mood

Derek Hansen, Life Fitness thought leader and expert in running, also expects to see cardio get a natural lift from the strength training boom