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MOTS-c has a short half-life (46 hours) and works best when AMPK is already primed by low ATP (fasted state, pre-training)

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L-Carnitine plays a vital role in lipid oxidation and energy production by transporting long-chain fatty acids to the mitochondrial matrix, where they can be oxidized (burned) to release energy

Haematological symptoms arise because B12 deficiency impairs red blood cell maturation, leading to megaloblastic anaemia