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[7] [8] Maintaining a healthy weight can potentially reduce the frequency and severity of diverticulitis episodes
However, if the A1c is 60 mg/mmol, or progressive increase in UACR despite appropriate therapy, eGFR 30% increase in serum creatinine within 3 months of starting SGLT2i, ACEi, or ARB, inability to achieve target BP, or signs/symptoms of another underlying kidney disease, such as glomerulonephritis
[4] [5] These medications also act on the brain's appetite centres, promoting feelings of fullness and reducing hunger signals
Recent research has added another layer of complexity
The hierarchy based on current clinical data places tirzepatide at the top (20.2% average loss), followed by semaglutide (13.7% average loss), then liraglutide (approximately 8% average loss)
