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These changes are caused by genetic and epigenetic changes in the tumor, and increased GSH was associated with epithelial-mesenchymal transition, local invasion, metastasis, and tumor survival [61, 62]

Age below 50 vs 50 years or older served as proxies for premenopausal and postmenopausal status, respectively, with a sensitivity analysis conducted to assess age and menopausal confounding

This observation suggests the importance of TRPM5 function in mediating triagonist-induced increases in insulin secretion and overall normoglycaemia