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Abstract Providing NO-system importance, we suggest that one single application of the NOS-blocker L-NAME may induce retinal ischemia in rats, and that the stable pentadecapeptide BPC 157 may be the therapy, since it may interact with the NO-system and may counteract various adverse effects of L-NAME application

The transcellular route takes the peptide directly through the epithelial cells

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For instance, the concomitant use of NSAIDs (non-steroidal anti-inflammatory drugs) can exacerbate kidney toxicity, which is a significant concern for those on tacrolimus therapy

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