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Clinicians should adopt an individualized approach, considering patient-specific factors such as age, reproductive plans, comorbidities, and tolerance
Greenlee H, Atkinson C, Stanczyk FZ, Lampe JW
Placebo in People With Type 2 Diabetes Insufficiently Controlled on Metformin (GetGoal-F1)
Another possibility is the existence of differences in the effect of high molecular weight versus low molecular weight peptides on GLP-1R signaling in the CNS [23]
For context, the Mounjaro FDA prescribing information lists injection-site reactions among the documented adverse events across the SURPASS trials at roughly 3-7% uncommon but consistent enough that a methodical approach matters from day one
D.FrydmanR
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