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Supplements containing iron, calcium, or magnesium can block the absorption of your medication

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Other systemic illnesses, such as diabetes and hyperthyroidism, or organ diseases affecting the liver and kidneys, can also contribute to deficiency by either preventing normal absorption or disrupting vitamin storage

BUT, if we have a deficiency in copper (which is used in the reaction that turns homocysteine into cystathione), then homocysteine can get stuck