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Ferroptosis, an iron-dependent non-apoptotic cell death driven by excessive lipid peroxidation, was first characterized by Dixon et al., in 2012 through studies on erastin and RAS-selective lethal compounds (Mahoney-Snchez et al., 2021

However, malnutrition and starvation are difficult to assess clinically and in particular protein-calorie malnutrition can co-exist with chronic alcohol use and with inter-current acute or chronic illness, which may independently or in concert increase the risk of paracetamol toxicity and confound the assertion that malnutrition per se increases the risk of paracetamol toxicity [6, 16, 73, 78,79,80,81,82,83]

[36] Acetylcysteine can be administered as a part of a complex molecule, thiamphenicol glycinate acetylcysteine, which also contains thiamphenicol, an antibiotic

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PLoS One 10 (6), e0127551