As a glutathione peroxidase, GPx1 functions in the detoxification of hydrogen peroxide, specifically by catalyzing the reduction of hydrogen peroxide to water
One of the rare (but potentially underdiagnosed) causes of anion gap metabolic acidosis is acquired 5-oxoprolinuria due to excessive Tylenol ingestion
Supported by: The Danish Agency for Science, the Danish Health Authority, the Danish Medicines Agency, the Danish Diabetes Association, and Novo Nordisk Foundation Disclosure: R.W
They are not licensed for human use in the UK and carry risks including fluid retention, insulin resistance, and joint discomfort
This has changed with some of the new medications that have recently become available
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