(DHFR = dihydrofolate reductase
Therapeutic is defined by the Australian Therapeutic Goods Administration (TGA) as: * Influencing, inhibiting or modifying a physiological process in people or animals
Romeo-Puertas et al., 2006)
The caprylate/chromatography manufacturing process was also investigated for its capacity to decrease the infectivity of an experimental agent of transmissible spongiform encephalopathy (TSE), considered as a model for the variant Creutzfeldt-Jakob disease (vCJD), and Creutzfeldt-Jakob disease (CJD) agents.(1) These studies provide reasonable assurance that low levels of vCJD/CJD agent infectivity, if present in the starting material, would be removed by the caprylate/chromatography manufacturing process
Ann Thorac Surg 101(4):1262-70, 2016
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