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This effect may be related to the promotion of neuronal survival, axonal growth, and synapse formation by Melanotan 2

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PPAR- deletion attenuates Cisplatin nephrotoxicity by modulating renal organic transporters MATE-1 and OCT-2

doi: 10.1161/01.ATV.0000258809.47285.07

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5 Regulation of adaptive immunity by innate immunity in vitiligo Vitiligo is an autoimmune disease driven by dysregulated adaptive immunity, where autoreactive CD8 + T cells selectively destroy melanocytes, leading to progressive skin depigmentation