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As expected, refeeding induced a rapid decline in ghrelin to similar levels in female and male WT and Tmprss2 / mice (Figure 2K)

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Participants received once-weekly subcutaneous injections of retatrutide at doses of 0.5 mg, 4 mg, 8 mg, or 12 mg, or placebo, over a 24-week treatment period, with gradual dose escalation to the target maintenance dose

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