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Researchers analyzed outcomes across the entire group regardless of whether patients stayed on therapy

doi:10.1007/s12020-020-02334-0 [25] Martnez Garca RM, Jimnez Ortega AI, Lpez Sobaler AM, Ortega RM

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Nonclinical Observations Repeat-dose animal studies reported reduced food intake and body-weight changes consistent with GLP-1 receptor agonism Rodent studies identified dose-dependent thyroid C-cell hyperplasia and embryo-fetal toxicity at relevant exposures, informing laboratory hazard assessments

Recent estimates indicate that about 5 million and 280 million people are affected by cocaine use disorder and alcohol use disorder, respectively