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PARAGON examined the impact of sacubitril-valsartan in with HFpEF (EF 45%) compared to valsartan

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If meaningful results are occurring at 1.0 mg or 1.7 mg with acceptable tolerability, some protocols maintain that lower dose rather than continuing to escalate

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Product Form and Specification IGF-1 LR3 is supplied as a white lyophilized powder in sterile, sealed vials