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Nasal spray delivery offers an appealing alternative, allowing peptides to absorb through nasal mucosa directly into systemic circulation while bypassing first-pass liver metabolism that destroys orally-administered peptides

doi: 10.1016/j.freeradbiomed.2015.09.007 37 MedzhitovR

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Figure 1 3.3 Effects of glutathione feeding on the activities of immunity-related enzymes in bullfrog serum As shown in Figure 2 , SOD activity was elevated and AKP activity was decreased in the serum of bullfrogs in the glutathione group compared to the FI group