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Researchers havent completely figured out the exact cause of IC, but some believe it stems from inflammation within various organs in the body (x)

Considering the vital role of energy requirement in the differentiation of intestinal epithelium, we extracted the differentially expressed metabolism-related genes and further examined their correlation with Satb2 expression in RNA-seq data from 43 adjacent colorectal cancer tissues in the Cancer Genome Atlas (TCGA)

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