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While it exists naturally in our body, external factors like pollution, UV rays, stress, lack of sleep, and age reduce its levels over time, leading to dullness, dark spots, uneven tone, and premature aging

In addition, it can also inhibit or deactivate the tyrosinase enzyme which supports melanin production, and help in the change from eumelanin to phaeomelanin production

In contrast, the nanoparticles NP4 had a much longer blood circulation half-life time of 2.97 h (Supplementary Fig

doi: 10.1038/nature04648

Crit Rev Toxicol 1999;29(3):283-330

3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) was obtained from Energy Chemical (Shanghai, China)