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Acknowledgements During the preparation of this manuscript, the authors used Grammarly for the purposes of improving English style and writing

2017;171:331345.e22

10.3390/jcm10040603 16

In general, the combined use of vitamin B 12 and folate is more effective than either alone

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Citation5 Both approaches offer a unique opportunity to delay the onset of age-related diseases and extend the healthspan, the period of life spent in good health