Selenium-Dependent Enzymes in Thyroid Metabolism The thyroid gland contains the highest concentration of selenium per gram of tissue in the human body, reflecting its fundamental role in regulating metabolism [1]
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Namely, the irreversible monoamine oxidase (MAO B) inhibition (i.e., pargyline) and subsequent serotonin substrate (L-tryptophan as a serotonin precursor) induced fore paw treading, hind limbs abduction, wet dog shake, and hypothermia followed by hyperthermia in rats, which commonly occur in serotonin syndrome [66]
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