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Keywords: Icotrokinra, Immune-mediated inflammatory disease, Interleukin-23, Oral peptide delivery, Oral systemic peptide, Peptide therapeutics Key Summary Points Introduction Immune-mediated inflammatory diseases (IMIDs), such as psoriasis, psoriatic arthritis, and inflammatory bowel disease (IBD), which includes Crohns disease and ulcerative colitis, encompass a heterogenous group of conditions associated with chronic inflammation [1]

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