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This creates a feedback loop where the worry about feeling unwell produces the very symptoms youre worried about

These include gastrointestinal symptoms (nausea, vomiting, diarrhoea, constipation), injection site reactions, and, rarely, pancreatitis (severe upper abdominal pain radiating to the back) or gallbladder problems

npj Metab Health Dis 3 , 6 (2025)

If you're not working with a doctor, how do you find the right protocol

Good: Systematic review of randomised controlled trials, randomised placebo controlled trial, or prospective cohort studies with or without concurrent controls plus good pathophysiological explanation

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