This potentially creates a vicious cycle leading to damage by free radicals unless the glutamatergic transmission is associated with increase in glutathione
% change in ROS production from a typical histogram is presented in Figure 3ii
In ALS patients, no significant differences in serum IL-2 levels versus control subjects were reported [82, 83] suggesting that this cytokine might have a limited input in the immune system response, at least in the early stage of disease (14.3 9.34 months disease duration in [83])
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