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Elevated levels of extracellular glutamate lead to the overactivation of Ca 2+ -permeable NMDARs, subsequent Ca 2+ overload, and excitotoxicity (Figure 1
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A variety of cellular properties will change in ECs after EndMT, such as increased permeability, enhanced migration, upregulated expression of some mesenchymal cellular markers, and enhanced ability to secret enzymes and to change the ECM environment
one vial covers about 7-15 days
Kempkes, M., Golka, K., Reich, S., Reckwitz, T