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[3] It is a ghrelin-receptor agonist it activates the growth hormone secretagogue receptor type 1a (GHSR-1a), the same receptor that endogenous ghrelin, the stomach-derived hunger hormone, binds
Clinical research in people with HIV-associated abdominal fat accumulation found that tesamorelin decreased visceral adipose tissue by about 15% to 20% over 6 to 12 months
Therefore, the two peptides may be used to provide a rapid onset of action with Ipamorelin and prolonged effects with CJC-1295
A 5-days-on / 2-off variant (dosing MondayFriday, resting the weekend) also appears in the research framing for those studying receptor-sensitivity preservation
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