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Long-Term Safety Evidence While many peptide therapies have been evaluated only in short-term trials, AOD-9604 benefits from long-term safety data extending to 24 weeks of continuous administration

Increases Energy Levels Low B12 can cause fatigue and weakness

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However, it means that this method may be more painful and may cause swelling and redness

While GLP-1 agonists may produce greater total weight loss, AOD-9604 more selectively targets fat tissue while preserving muscle mass

Comment: Several commenters did not support the security risk analysis measure modification and expressed concern that the proposed modification is duplicative or unnecessarily burdensome because MIPS eligible clinicians are already required by the HIPAA Security Rule to conduct regular security risk analyses and address identified vulnerabilities