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Oral version: 13.1% weight loss in 12 weeks Injectable: 22% in 36 weeks (at 20 mg), on par with Lillys triple agonist

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Clinical practice guidelines for healthy eating for the prevention and treatment of metabolic and endocrine diseases in adults: cosponsored by the American Association of Clinical Endocrinologists/the American College of Endocrinology and the Obesity Society

However, metformin is oral, inexpensive, and has an extensive safety record, making it the preferred initial therapy

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