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The significant improvement was found in rats pretreated with EW 1 fraction of S

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Thangavelu G, Andrejeva G, Bolivar-Wagers S, Jin S, Zaiken MC, Loschi M, et al

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Bioavailability following subcutaneous injection is estimated at approximately 80%, substantially higher than oral administration, where peptide degradation in the gastrointestinal tract limits systemic exposure

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