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Initially, a single dose of 10 g/kg (absolute dose range 0.71.2 mg) was administered to six subjects (three with severe RI and three with ESRD) but, based on the frequency and severity of gastrointestinal adverse effects, the 10 g/kg dose was not considered a tolerable starting dose
One in 6 (17%) of those with a semaglutide/tirzepatide-type prescription also had history of a mental health condition other than alcohol use disorder versus 9% in those without a prescription
All authors contributed intellectually to this study and critically revised the scientific content of the manuscript
