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HS is strongly associated with immune abnormalities, oxidative damage, 1 It is characterized by painful follicular occlusions, primarily at intertriginous locations, which can further manifest as nodules, abscesses, skin tunnels, and fibrosis

In the setting of NET, liraglutide seems to be beneficial in treating panNETs by inhibiting in vivo and in vitro the PI3K/AKT pathway with a reduction of metastasis, and cancer growth [52, 53]

They cause the nuclear factor kappa B (NFB) pathway to activate and release IFN alpha, leading to autoantibody formation by B cells against the nuclear antigen of apoptosis cells

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