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the higher oxygen affinity of HbF, even in the presence of 2,3-BPG, promotes efficient transfer of O 2 across the placenta from HbA to HbF (see Chapter 5 )

Transitions to lentigo maligna can be fluid

A 2024 observational study raised questions about whether GLP-1 receptor agonists as a class may be associated with an increased risk of GORD-related conditions

Triple, quadruple and quintuple agonists are now in development, as is an expanded range of oral formulations

Packer M, Anker SD, Butler J, Filippatos G, Pocock SJ, Carson P, Januzzi J, Verma S, Tsutsui H, Brueckmann M, Jamal W, Kimura K, Schnee J, Zeller C, Cotton D, Bocchi E, Bohm M, Choi DJ, Chopra V, Chuquiure E, Giannetti N, Janssens S, Zhang J, Gonzalez Juanatey JR, Kaul S, Brunner-La Rocca HP, Merkely B, Nicholls SJ, Perrone S, Pina I, Ponikowski P, Sattar N, Senni M, Seronde MF, Spinar J, Squire I, Taddei S, Wanner C, Zannad F

doi: 10.1089/ars.2010.3275