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treatment with a selective ER antagonist (and not selective ER or GPER1 antagonists) abolished the beneficial effect of E2 on liver fibrosis scores (29)

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Owing to the absence of -12 and -15 desaturase enzymes, which are necessary for forming carbon-carbon double bonds outside the -12 and -15 carbons, these precursors cannot be produced de novo ( Figure 1 ) in livestock, such as chickens, hence, they should be supplemented in the diet (Ngcobo et al., 2021)

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doi:10.1074/jbc.273.48.31853

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