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While Lipinskis Rule of Five suggested that molecules with a molecular weight less than 500 Da have better chances of crossing the BBB than larger molecules, its essential to note that Lipinski himself cautioned against applying these rules to certain categories of molecules, such as anti-parasitic drugs

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BioBoost contains methionine, inositol, choline, and B vitamins, among other essential nutrients

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Overview over study participants

The guinea pigs were treated with an intra-peritoneal or intra-tympanic dose of aminothiol PrC-210 (3-(methyl-amino)-2-((methylamino)methyl)propane-1-thiol) a week before inner ear irradiation (3000cGy) [87]