glp 1 birth defects GLP-1-Mediated Pregnancy and Neonatal Complications in Mice Glucagon-like peptide-1 receptor agonist use

134 , e175634 (2024)

doi: 10.1002/jnr.24706 157 McCleanPLHolscherC

Keywords: GLP1, obesity, adolescents, GLP1 dual agonist, GLP1 triple agonist, diabetes Introduction The Growing Burden of Adolescent Obesity With prevalence rates rising sharply over the past few decades, adolescent obesity has emerged as a major global public health challenge

As a diabetes drug, Zepbound is sold under the brand name Mounjaro, as the two medications contain the same active ingredient, tirzepatide

This double-blind, placebo-controlled study randomized adults with a BMI 30 or 27 plus at least one obesity-related comorbidity (excluding diabetes) who had achieved 5% weight loss after 12 weeks of lifestyle modification to receive tirzepatide or placebo weekly for 72 weeks

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