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Epitalon also influences the neuroendocrine system by stimulating nocturnal melatonin release from the pineal gland, thereby normalizing circadian hormone rhythms in aged subjects [3]

They are signal sequences of PhoA [6] , LTB [7] , and StII [8] , named signal peptide 1 (SP1), signal peptide 2 (SP2), and signal peptide 3 (SP3), respectively

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