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The anthocyanins in blueberries, especially delphinidin 3-rutinoside, stimulate L-cells in the intestine to release endogenous GLP-1

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Basic Workflow: -Sample injection into LC system -Separation of components via chromatography -Ionization (typically ESI) -Mass detection (MS) -Optional fragmentation (MS/MS) for structural analysis Used extensively in pharmaceutical, biotech, and proteomics research 4

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Long-term treatment with a glucagon-like peptide-1 receptor agonist reduces ethanol intake in male and female rats