As NAc is also an important brain region associated with GLP-1-induced feeding suppression, further electrophysiological studies are necessary to explore the contribution of glutamatergic neurotransmission to endogenously released GLP-1-induced suppression of high-fat food intake in the VTA
Ileus is a serious condition involving slowed or stopped intestinal movement
Individuals with type 2 diabetes have higher rates of osteoarthritis, and obesity itself is a major risk factor for joint disease
Carnitine plays an essential role in the way that mitochondria use fats for fuel, and the study showed that mice deficient in a carnitine transporter, SLC25A45, didnt lose weight as easily on a GLP-1 RA medication.[ref] Related article: Carnitine genes GLP-1 Beyond Weight Loss: Heart Disease, Alzheimers, Cancer, and Immunity Recent studies show that the benefits of GLP-1 RA medications extend beyond weight loss
Pharmacol Res (2020) 152:104615
Counseling should emphasize shared decisionmaking and evidencebased care