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Headache from AOD 9604 Mild to moderate headache is the most commonly reported AOD 9604 side effect, occurring in roughly 70% of subjects in clinical trials at rates comparable to placebo

Response: We appreciate the additional information provided by the commenters regarding the clinical activities associated with CA023

Oxidative stress can damage the RNA machine involved in transcription and translation in bacteria, a critical function in bacterial survival (15)

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A 2025 meta-analysis verified that stopping causes a substantial metabolic rebound, with obese patients seeing an average weight gain of 5.63 kg as well as declines in blood pressure, waist circumference, and glycaemic control

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