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It consists of HGH residues 176191, with a tyrosine in place of the phenylalanine at the N-terminal end

Gene therapy involves intra-articular injection of vectors into the diseased joint to promote the apoptosis of target cells or continuously express their products against pathogenic factors ( Figure 5 )

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As such the overall impact of the manuscript would benefit greatly by detailed editing and potential re-organization. Response: As per your suggestion, we have replaced the section on requirements and detection of dimers with a reference to the original IUPHAR publication

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Recommended areas for application:Above wrists on inside of forearms, inner thighs, lower back